Proteomics for Drug Discovery : Methods and Protocols
ISBN13 | 9781493972005 |
Binding | PAPERBACK |
Author | IULIA M. LAZAR |
Language | ENGLISH |
Publisher | HUMANA PRESS |
Published Year | 2017 |
Country of Origin | India |
13874.00
This book reflects the drug development community?? interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico?lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful?Methods in Molecular Biology?series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.?Practical and authoritative,?Proteomics for Drug Discovery: Methods and Protocols?aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu.