Proteomics for Drug Discovery : Methods and Protocols

   In stock
SKU
BK0075420
ISBN13 9781493972005
Binding PAPERBACK
Author IULIA M. LAZAR
Language ENGLISH
Publisher HUMANA PRESS
Published Year 2017
Country of Origin India

13874.00

This book reflects the drug development community?? interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico?lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful?Methods in Molecular Biology?series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.?Practical and authoritative,?Proteomics for Drug Discovery: Methods and Protocols?aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu.